USMLE Step 1

The first part, USMLE step 1, is a multiple choice exam consisting of about 300 questions taken over eight hours in one day at the test center. The step 1 covers all of the basic sciences - Anatomy, Biochemistry, Physiology, statistics, Behavioural science, microbiology, pharmacology, pathology, ethics - and it is typically taken in the first half of the medical school curriculum at a time when these subjects have been covered. Scores are reported as two digit (NOT %) and three digit scores. The percentage required to pass is determined based not on a population curve, but on the relative difficulty of the items as determined by the test committee. That pass % is then set as being equal to a two digit score of 75. The mean three digit score is 200. Many programs look for two digit scores of at least 80-85 for entry. 66% of international medical graduates pass this exam with each sitting, while 91% of US medical students do.

Step 1 Content outlines are as followed: General Principles, Hematopoietic and Lylmphoreticular Systems, Central and Peripheral Nervous Systems, Skin and related Connetive Tissue, Musculoskeletal system, Respiratory system, Cardiovascular system, Gastrointestinal system, Renal/Urinary system, reproductive system, and endocrine system.

STEP 1 Test Question Format

Single One Best Answer QuestionsStep 1 includes only single questions with one best answer. This is the traditional, most frequently used multiple-choice format. These items consist of a statement or question followed by three to eleven response options arranged in alphabetical or logical order. A portion of the questions involves interpretation of graphic or pictorial materials. The response options for all questions are lettered (eg, A, B, C, D, E). Examinees are required to select the best answer to the question. Other options may be partially correct, but there is only ONE BEST answer.

Strategies for Answering Single One Best Answer Test Questions

Read each question carefully. It is important to understand what is being asked.
Try to generate an answer and then look for it in the option list.
Alternatively, read each option carefully, eliminating those that are clearly incorrect.
Of the remaining options, select the one that is most correct.
If unsure about an answer, it is better to guess since unanswered questions are automatically counted as wrong answers.

Example Question 1
A 32-year-old woman with type 1 diabetes mellitus has had progressive renal failure over the past 2 years. She has not yet started dialysis. Examination shows no abnormalities. Her hemoglobin concentration is 9 g/dL, hematocrit is 28%, and mean corpuscular volume is 94 µm3. A blood smear shows normochromic, normocytic cells. Which of the following is the most likely cause?

A. Acute blood loss
B. Chronic lymphocytic leukemia
C. Erythrocyte enzyme deficiency
D. Erythropoietin deficiency
E. Immunohemolysis
F. Microangiopathic hemolysis
G. Polycythemia vera
H. Sickle cell disease
I. Sideroblastic anemia
J. b-Thalassemia trait

(Answer D)

Orientation Materials

Application materials